Age and Melanocytic Lesions

Surg Oncol Clin N Am. 2020 Jul;29(3):369-386. doi: 10.1016/j.soc.2020.02.005.

Abstract

Age plays a dynamic role in incidence, presentation, and extent of disease for cutaneous melanoma. Even within the spectrum of juvenile melanoma, there exists a range of spitzoid and nonspitzoid melanocytic and melanoma lesions. Spitzoid melanomas, a more favorable disease in juvenile patients, are malignant lesions and require treatment as such. Lymph node metastases in melanoma occur at lower rates in older patients compared with younger counterparts, yet the rate of metastases is still high. Age appears to play an important role in the development and progression of melanoma, and understanding the differences across age populations is important when counseling patients.

Keywords: Adolescent melanoma; Lymph node metastases; Melanocytic lesions and age; Pediatric melanoma; Spitz nevi.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Humans
  • Lymphatic Metastasis
  • Melanoma / pathology*
  • Nevus, Epithelioid and Spindle Cell / pathology*
  • Prognosis
  • Skin Neoplasms / pathology*