Successful management of giant condyloma acuminatum of vulva with the combination of surgery and photodynamic therapy: Report of two cases

Photodiagnosis Photodyn Ther. 2020 Sep:31:101847. doi: 10.1016/j.pdpdt.2020.101847. Epub 2020 May 30.

Abstract

Patients with condylomata acuminata of the vulva usually have increased difficulty to achieve complete response to treatment and also have a higher risk for disease recurrence. Treatment for this disease varies, including surgical excision, cryotherapy, electrocautery, CO2 laser therapy, topical therapy, and photodynamic therapy (PDT), but none of these alone provides a satisfactory outcome, especially for giant condyloma acuminatum (GCA). We reported two cases of GCA successfully cured with surgical removal, electrocautery and photodynamic therapy.

Keywords: Combination therapy; Giant condyloma acuminatum; Photodynamic therapy.

Publication types

  • Case Reports

MeSH terms

  • Buschke-Lowenstein Tumor* / drug therapy
  • Condylomata Acuminata* / drug therapy
  • Female
  • Humans
  • Neoplasm Recurrence, Local / drug therapy
  • Photochemotherapy* / methods
  • Photosensitizing Agents / therapeutic use
  • Vulva

Substances

  • Photosensitizing Agents