Early instauration granulomatous pneumonitis associated with use of etanercept in seronegative spondyloarthropathy: Case report

Respir Med Case Rep. 2020 May 18:30:101079. doi: 10.1016/j.rmcr.2020.101079. eCollection 2020.

Abstract

Spondyloarthropathies are a group of chronic inflammatory disorders that involve the joints of the axial skeleton, peripheral joints and have extra-articular manifestations. Treatment includes inhibitors of tumor necrosis factor α. Currently there are five approved inhibitors: a soluble receptor, Etanercept and four monoclonal. Etanercept has very low toxicity with pulmonary adverse reactions being very rare. We present the case of a patient who developed respiratory symptoms and pulmonary infiltrates of rapid evolution after the third dose of treatment with Etanercept.

Keywords: Anti-TNF; Case report; Etanercept; Pulmonary granulomatosis; Spondyloarthropathy; TNF-α.

Publication types

  • Case Reports