Soft drugs: design principles, success stories, and future perspectives

Expert Opin Drug Metab Toxicol. 2020 Aug;16(8):645-650. doi: 10.1080/17425255.2020.1777280. Epub 2020 Jun 20.

Author

Peter Buchwald¹

Affiliation

¹ Diabetes Research Institute and Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami , Miami, FL, USA.

PMID: 32476535
DOI: 10.1080/17425255.2020.1777280

No abstract available

Keywords: Antedrug; drug metabolism; esterases; methylphenidate; prodrug; sofpironium; therapeutic index; toxic metabolite.

Publication types

Editorial

MeSH terms

Drug Design*
Drug Development*
Humans
Pharmaceutical Preparations / administration & dosage
Pharmaceutical Preparations / metabolism*

Substances

Pharmaceutical Preparations