Mucosa microbiome of gastric lesions: Fungi and bacteria interactions

Zikai Wang; Rongrong Ren; Yunsheng Yang

doi:10.1016/bs.pmbts.2020.03.004

Mucosa microbiome of gastric lesions: Fungi and bacteria interactions

Prog Mol Biol Transl Sci. 2020:171:195-213. doi: 10.1016/bs.pmbts.2020.03.004. Epub 2020 Apr 25.

Authors

Zikai Wang¹, Rongrong Ren¹, Yunsheng Yang²

Affiliations

¹ Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China.
² Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China. Electronic address: sunny301ddc@126.com.

PMID: 32475522
DOI: 10.1016/bs.pmbts.2020.03.004

Abstract

Many components of the gastric non-Helicobacter pylori microbiota have been identified recently thanks to advances in DNA sequencing techniques. Several lines of evidence support the hypothesis that the gastric microbiome is essential for gastric disorders such as gastric cancer. Microbial interactions impact the pathophysiology of various gastric disorders. This chapter provides an overview of recent findings regarding general gastric microbial community profiling, microbial interactions in the stomach, and microbial characteristics in various gastric disorders.

Keywords: Bacterial microbiota; Dysbiosis; Fungal microbiota; Gastric disorders; Helicobacter pylori; Microbial interactions; Microbiome; Microbiota; Mucosa; Stomach.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Bacteria / metabolism*
Fungi / physiology*
Gastrointestinal Microbiome*
Humans
Microbial Interactions*
Stomach / microbiology*
Stomach Diseases / microbiology*