Green Tea, A Medicinal Food with Promising Neurological Benefits

Curr Neuropharmacol. 2021;19(3):349-359. doi: 10.2174/1570159X18666200529152625.

Abstract

Neurological disorders and their sequelae, as of the widespread and critical humans' complications, affect the body's nervous systems, organ functions, and behaviors. According to WHO, neurological disorders are currently predicted to affect more than one billion people globally. It is well-established that complementary medicine is one of the high accepted interventions that could have been considered for the management of neurological ailments. The current review aimed to compile all the crucial data reporting the investigation on the conspicuous intervention of green tea (made of Camellia sinensis) and related lead compounds (especially l-theanine, epigallocatechin- 3-gallate, epicatechin-3-gallate, epicatechin, and epigallocatechin) for their neurological activities, mechanisms of action, and clinical properties. According to the documents, green tea exhibits antidepressant, anti-neurodegenerative (e.g., anti-Parkinson and anti-Alzheimer), as well as neuroprotective effects.Chief among them, for offering novel work, it is worth focusing on several related assessments with great attention to more extensive standardized clinical trials, and subsequently more in-depth pharmacokinetic studies to safely introduce this beneficial medicinal food as a neuro-effective agent.

Keywords: Camellia sinensis; complementary medicine; green tea; neurological disorders; polyphenol; review.

Publication types

  • Review

MeSH terms

  • Camellia sinensis
  • Humans
  • Neuroprotective Agents / therapeutic use
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Tea*

Substances

  • Neuroprotective Agents
  • Plant Extracts
  • Tea