COVID-19 and fertility: a virtual reality

Reprod Biomed Online. 2020 Aug;41(2):157-159. doi: 10.1016/j.rbmo.2020.05.001. Epub 2020 May 8.

Abstract

The COVID-19 pandemic is an extraordinary global situation, and all countries have adopted their own strategies to diminish and eliminate the spread of the virus. All measures are in line with the recommendations provided by the World Health Organization. Scientific societies, such as the European Society for Human Reproduction and Embryology and American Society for Reproductive Medicine, have provided recommendations and guidance to overcome and flatten the growing curve of infection in patients who undergo IVF treatments. Although there is as yet no evidence that the virus causing COVID-19 might have negative effects on IVF outcomes, fertility treatments have been postponed in order to support healthcare systems by avoiding placing them under additional stress. The possibility of the virus affecting sperm function and egg performance cannot be excluded. In addition, an indirect effect of the virus on gametes and embryos during their manipulation cannot be ruled out. This commentary aims to provide some ideas on the possible effect of the virus on gametes and embryos, as well as how it could affect the normal functioning of the embryology laboratory.

Keywords: COVID-19; Clinical embryology; Fertility.

MeSH terms

  • Betacoronavirus* / physiology
  • COVID-19
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / prevention & control*
  • Embryo, Mammalian / virology
  • Female
  • Fertility Clinics / statistics & numerical data
  • Fertility*
  • Fertilization in Vitro / methods
  • Fertilization in Vitro / statistics & numerical data
  • Humans
  • Male
  • Oocytes / virology
  • Pandemics / prevention & control*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / prevention & control*
  • Pregnancy
  • Reproductive Techniques, Assisted / statistics & numerical data*
  • SARS-CoV-2
  • Spermatozoa / virology
  • Treatment Outcome