SARS-CoV-2 Phylogenetic Analysis, Lazio Region, Italy, February-March 2020

Emerg Infect Dis. 2020 Aug;26(8):1842-1845. doi: 10.3201/eid2608.201525. Epub 2020 May 27.

Abstract

We report phylogenetic and mutational analysis of severe acute respiratory syndrome coronavirus 2 virus strains from the Lazio region of Italy and provide information about the dynamics of virus spread. Data suggest effective containment of clade V strains, but subsequently, multiple waves of clade G strains were circulating widely in Europe.

Keywords: COVID-19; Italy; SARS-CoV-2; coronavirus disease; full genome sequence; phylogenetic tree; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Betacoronavirus / classification
  • Betacoronavirus / genetics*
  • Betacoronavirus / pathogenicity
  • Bronchoalveolar Lavage Fluid / virology
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques / methods
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / transmission*
  • Coronavirus Infections / virology
  • Female
  • High-Throughput Nucleotide Sequencing
  • Hospitalization
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Mutation
  • Nasopharynx / virology
  • Pandemics*
  • Phylogeny*
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / transmission*
  • Pneumonia, Viral / virology
  • Prospective Studies
  • RNA, Viral / genetics*
  • Real-Time Polymerase Chain Reaction
  • SARS-CoV-2
  • Severity of Illness Index
  • Time Factors

Substances

  • RNA, Viral