Cronkhite-Canada syndrome: report of a rare case and review of the literature

J Int Med Res. 2020 May;48(5):300060520922427. doi: 10.1177/0300060520922427.

Abstract

Cronkhite-Canada syndrome is rarely encountered in clinical practice. Notably, most patients with Cronkhite-Canada syndrome exhibit hypoalbuminemia. Because the cause of Cronkhite-Canada syndrome is unknown, no specific treatment method has been established. Here, we describe a 59-year-old woman with Cronkhite-Canada syndrome in whom clinical manifestations were considerably relieved after treatment with prednisone.

Keywords: Cronkhite–Canada syndrome; blood protein disorders; hypoalbuminemia; intestinal polyposis; metabolic diseases; prednisone.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Endoscopy, Gastrointestinal
  • Female
  • Gastric Mucosa / diagnostic imaging
  • Gastric Mucosa / immunology
  • Gastric Mucosa / pathology
  • Humans
  • Hypoalbuminemia / blood
  • Hypoalbuminemia / diagnosis
  • Hypoalbuminemia / drug therapy
  • Hypoalbuminemia / immunology*
  • Intestinal Mucosa / diagnostic imaging
  • Intestinal Mucosa / immunology
  • Intestinal Mucosa / pathology
  • Intestinal Polyposis / complications
  • Intestinal Polyposis / diagnosis*
  • Intestinal Polyposis / drug therapy
  • Intestinal Polyposis / immunology
  • Middle Aged
  • Prednisone / therapeutic use*
  • Serum Albumin, Human / analysis
  • Treatment Outcome

Substances

  • Prednisone
  • Serum Albumin, Human