Beclomethasone Has Lesser Suppressive Effects on Inflammation and Antibacterial Immunity Than Fluticasone or Budesonide in Experimental Infection Models

Chest. 2020 Sep;158(3):947-951. doi: 10.1016/j.chest.2020.05.531. Epub 2020 May 23.

Authors

Faisal Kamal¹, Nicholas Glanville¹, Wangmingyu Xia¹, Eteri Bakhsoliani¹, Julia Aniscenko¹, Nathan W Bartlett², Michael R Edwards¹, Sebastian L Johnston¹, Aran Singanayagam³

Affiliations

¹ National Heart and Lung Institute, Imperial College, London, UK.
² Faculty of Health and Medicine and Priority Research Centre for Healthy Lungs, University of Newcastle, Australia.
³ National Heart and Lung Institute, Imperial College, London, UK. Electronic address: a.singanayagam@imperial.ac.uk.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Administration, Inhalation
Animals
Anti-Inflammatory Agents / pharmacology*
Beclomethasone / pharmacology
Budesonide / pharmacology
Disease Susceptibility
Female
Fluticasone / pharmacology
Mice
Mice, Inbred C57BL
Pneumonia, Pneumococcal / etiology*
Pneumonia, Pneumococcal / prevention & control*
Pulmonary Disease, Chronic Obstructive / drug therapy
Streptococcus pneumoniae

Substances

Anti-Inflammatory Agents
Budesonide
Fluticasone
Beclomethasone

Grants and funding