A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus

Fei Wang; Qumiao Xu; Zhenkun Zhuang; Ziyi Li; Qianqian Gao; Yaling Huang; Yonglun Luo; Xiuqing Zhang; Linnan Zhu; Cheng-Chi Chao

doi:10.1038/s41423-020-0466-z

A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus

Cell Mol Immunol. 2021 May;18(5):1326-1328. doi: 10.1038/s41423-020-0466-z. Epub 2020 May 25.

Authors

Fei Wang^#^{1

2

3}, Qumiao Xu^#^{2

4

5}, Zhenkun Zhuang^#^{1

2

6}, Ziyi Li^{2

7}, Qianqian Gao^{2

4}, Yaling Huang^{2

4}, Yonglun Luo^{2

3}, Xiuqing Zhang^{8

9

10

11

12}, Linnan Zhu^{13

14

15}, Cheng-Chi Chao^{16

17

18

19}

Affiliations

¹ BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, 518083, China.
² BGI-Shenzhen, Shenzhen, 518083, China.
³ Department of Biomedicine, Aarhus University, 8000, Aarhus, Denmark.
⁴ China National GeneBank, BGI-Shenzhen, Shenzhen, 518120, China.
⁵ Shenzhen Key Laboratory of Genomics, Beishan Industrial Zone, Shenzhen, 518083, China.
⁶ School of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
⁷ Northwest A & F University, Yangling, 712100, Shaanxi, China.
⁸ BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, 518083, China. zhangxq@genomics.cn.
⁹ BGI-Shenzhen, Shenzhen, 518083, China. zhangxq@genomics.cn.
¹⁰ China National GeneBank, BGI-Shenzhen, Shenzhen, 518120, China. zhangxq@genomics.cn.
¹¹ Shenzhen Key Laboratory of Genomics, Beishan Industrial Zone, Shenzhen, 518083, China. zhangxq@genomics.cn.
¹² Guangdong Enterprise Key Laboratory of Human Disease Genomics, Beishan Industrial Zone, Shenzhen, 518083, China. zhangxq@genomics.cn.
¹³ BGI-Shenzhen, Shenzhen, 518083, China. zhulinnan@genomics.cn.
¹⁴ Shenzhen Key Laboratory of Genomics, Beishan Industrial Zone, Shenzhen, 518083, China. zhulinnan@genomics.cn.
¹⁵ Guangdong Enterprise Key Laboratory of Human Disease Genomics, Beishan Industrial Zone, Shenzhen, 518083, China. zhulinnan@genomics.cn.
¹⁶ BGI-Shenzhen, Shenzhen, 518083, China. chengchic@abvisioninc.com.
¹⁷ Shenzhen Key Laboratory of Genomics, Beishan Industrial Zone, Shenzhen, 518083, China. chengchic@abvisioninc.com.
¹⁸ Guangdong Enterprise Key Laboratory of Human Disease Genomics, Beishan Industrial Zone, Shenzhen, 518083, China. chengchic@abvisioninc.com.
¹⁹ AbVision, Inc, Milpitas, CA, USA. chengchic@abvisioninc.com.

^# Contributed equally.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

CD8-Positive T-Lymphocytes / immunology*
Cell Engineering*
Cytomegalovirus / immunology*
Humans
Peptides / immunology
Receptors, Antigen, T-Cell / metabolism
Single-Cell Analysis*

Substances

Peptides
Receptors, Antigen, T-Cell

Grants and funding

201904910476/China Scholarship Council (CSC)