In a post hoc analysis of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose mothers had been treated with the drug had higher prevalence of macrolide-resistance genes msr(A) and ermC at 28 days but not at 12 months. The 2 genes were positively associated in the nasopharynx.
Clinical trials registration: NCT1800942.
Trial registration: ClinicalTrials.gov NCT01800942.
Keywords: ermC; msr(A); azithromycin; NPS; The Gambia.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.