Association between Obesity and Omega-3 Status in Healthy Young Women

Nutrients. 2020 May 20;12(5):1480. doi: 10.3390/nu12051480.

Abstract

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential for healthy development and protect against metabolic disease. However, individuals with obesity may be pre-disposed to experiencing lower n-3 PUFA status than normal-weight individuals. This cross-sectional study examined the relationship between the omega-3 index (O3I), body mass index (BMI) and dietary intake in healthy young women (n = 300; age = 18-35 y), a group not previously focused on. Intake was adjusted for energy using the residuals method, and associations were explored using independent t-tests and Pearson's correlations. Participants with obesity were found to have significantly lower O3I than normal-weight participants (p < 0.0001); however, no significant differences were observed in mean n-3 PUFA intakes. Even so, energy-adjusted intakes of n-3 PUFAs, with the exception of alpha-linolenic acid, were significantly correlated with O3I. This study demonstrates that O3I is influenced by both BMI and diet in young women; however the relationship between these two variables may be complex. Current intakes of n-3 PUFA observed in young women may not be effective in achieving target O3I levels in those with obesity, and further research is needed to find effective ways of improving n-3 PUFA status in a group already at increased risk of metabolic disease.

Keywords: n-3 PUFA; obesity; omega-3; omega-3 index; young women.

MeSH terms

  • Adolescent
  • Adult
  • Body Mass Index
  • Cross-Sectional Studies
  • Diet
  • Fatty Acids, Omega-3 / blood*
  • Female
  • Humans
  • Obesity / metabolism*
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Fatty Acids, Omega-3