Ion Channels of Nociception

Int J Mol Sci. 2020 May 18;21(10):3553. doi: 10.3390/ijms21103553.

Abstract

The special issue "Ion Channels of Nociception" contains 13 articles published by 73 authors from different countries united by the main focusing on the peripheral mechanisms of pain. The content covers the mechanisms of neuropathic, inflammatory, and dental pain as well as pain in migraine and diabetes, nociceptive roles of P2X3, ASIC, Piezo and TRP channels, pain control through GPCRs and pharmacological agents and non-pharmacological treatment with electroacupuncture.

Keywords: ASIC; P2X3; Piezo channels; TRPA1; TRPV1; ion channels; migraine; nociception; pain; sensory neurons; tooth pain.

Publication types

  • Editorial
  • Introductory Journal Article

MeSH terms

  • Animals
  • Humans
  • Ion Channels / physiology*
  • Migraine Disorders / metabolism
  • Migraine Disorders / physiopathology
  • Nociception*
  • Pain / metabolism
  • Pain / physiopathology
  • Pain Management
  • TRPA1 Cation Channel / physiology
  • TRPV Cation Channels / physiology

Substances

  • Ion Channels
  • TRPA1 Cation Channel
  • TRPV Cation Channels