COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis

Diabetes Metab Syndr. 2020 Jul-Aug;14(4):683-685. doi: 10.1016/j.dsx.2020.05.021. Epub 2020 May 12.

Abstract

Objective: The objective of this study was to evaluate the pooled estimate of diabetes prevalence in young (<50 years) versus elderly (>50 years) COVID-19 cohorts.

Methods: Studies published between December-2019 and March-2020 reporting demographic and clinical characteristics of COVID-19 cases were identified. A total of 11 studies included accounting for 2084 COVID-19 patients.

Results: The overall prevalence of diabetes in COVID-19 patients with a mean age>50 years was 13.2%, whereas studies with relatively younger patients (mean age <50 years) had a pooled prevalence of 9.0% CONCLUSION: The overall prevalence of diabetes in COVID-19 patients was found to be 13.2% with studies including relatively elderly patients showing higher rates of diabetes. The intermingled effects of diabetes with other cardiovascular comorbidities warrant age-specific outcomes data including the impact of ongoing antidiabetic treatment.

Keywords: Antidiabetic treatment; COVID-19; Diabetes mellitus; Elderly; Prevalence; Type-2 diabetes.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Aged
  • Betacoronavirus / pathogenicity
  • COVID-19
  • Comorbidity
  • Coronavirus Infections / complications*
  • Coronavirus Infections / immunology
  • Coronavirus Infections / physiopathology*
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Guidelines as Topic
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / immunology
  • Pneumonia, Viral / physiopathology*
  • Prevalence
  • Risk Factors
  • SARS-CoV-2

Substances

  • Hypoglycemic Agents