Requirements for PARP-1 covalent crosslinking to DNA (PARP-1 DPC)

Rajendra Prasad; Julie K Horton; Samuel H Wilson

doi:10.1016/j.dnarep.2020.102850

Requirements for PARP-1 covalent crosslinking to DNA (PARP-1 DPC)

DNA Repair (Amst). 2020 Jun:90:102850. doi: 10.1016/j.dnarep.2020.102850. Epub 2020 Apr 28.

Authors

Rajendra Prasad¹, Julie K Horton¹, Samuel H Wilson²

Affiliations

¹ Genome Integrity and Structural Biology Laboratory, NIEHS, National Institutes of Health, 111 T.W. Alexander Drive, Research Triangle Park, North Carolina, 27709, USA.
² Genome Integrity and Structural Biology Laboratory, NIEHS, National Institutes of Health, 111 T.W. Alexander Drive, Research Triangle Park, North Carolina, 27709, USA. Electronic address: wilson5@niehs.nih.gov.

No abstract available

Keywords: AP site/abasic site, apurinic/apyrimidinic site; BER, base excision repair; DPC, DNA-protein crosslink; PARP-1, poly(ADP-ribose) polymerase 1.

Publication types

Research Support, N.I.H., Intramural
Review

MeSH terms

DNA / chemistry
DNA / metabolism
DNA Adducts
DNA Damage*
DNA Repair*
Humans
Poly (ADP-Ribose) Polymerase-1 / chemistry
Poly (ADP-Ribose) Polymerase-1 / metabolism*

Substances

DNA Adducts
DNA
PARP1 protein, human
Poly (ADP-Ribose) Polymerase-1

Publication types

MeSH terms

Substances

Grants and funding