Feasibility and Safety of Sac Embolization Using N-Butyl Cyanoacrylate in Emergency Endovascular Aneurysm Repair for Ruptured Abdominal Aortic Aneurysms or Isolated Iliac Artery Aneurysms

J Endovasc Ther. 2020 Oct;27(5):828-835. doi: 10.1177/1526602820923954. Epub 2020 May 21.

Abstract

Purpose: To evaluate the feasibility and safety of sac embolization with N-butyl cyanoacrylate (NBCA) in emergency endovascular aneurysm repair (EVAR) for ruptured abdominal aortic aneurysm (AAA) and iliac artery aneurysm (IAA) in comparison to EVAR without sac embolization.

Materials and methods: Between February 2012 and December 2019, among 44 consecutive patients with ruptured AAA or IAA, 29 underwent EVAR. Of these, 22 patients (median age 77.5 years; 18 men) had concomitant sac embolization using NBCA; the remaining 7 patients (median age 88 years; 6 men) underwent EVAR without sac embolization and form the control group. The technical success, clinical success (hemodynamic stabilization), procedure-related complications, and mortality were compared between the groups.

Results: All EVAR procedures and embolizations were successful. The clinical success rates in the NBCA and control groups were 95% (21/22) and 71% (5/7), respectively (p=0.14). There was no complication related to the procedure. Type II endoleak occurred in 4 of 21 patients (19%) in the NBCA group vs none of the control patients. One patient (5%) died in the NBCA group vs 3 (43%) in the controls (p=0.034).

Conclusion: Sac embolization using NBCA in emergency EVAR appears to be feasible and safe for ruptured AAA and IAA.

Keywords: N-butyl cyanoacrylate; abdominal aortic aneurysm; emergency; endovascular aneurysm repair; glue; hemodynamic stabilization; iliac artery aneurysm; ruptured aneurysm; sac embolization.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Aortic Aneurysm, Abdominal / physiopathology
  • Aortic Aneurysm, Abdominal / therapy*
  • Aortic Rupture / diagnostic imaging
  • Aortic Rupture / physiopathology
  • Aortic Rupture / therapy*
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Embolization, Therapeutic* / adverse effects
  • Emergencies
  • Enbucrilate / administration & dosage*
  • Enbucrilate / adverse effects
  • Endovascular Procedures* / adverse effects
  • Feasibility Studies
  • Female
  • Humans
  • Iliac Aneurysm / diagnostic imaging
  • Iliac Aneurysm / physiopathology
  • Iliac Aneurysm / therapy*
  • Male
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome

Substances

  • Enbucrilate