68Ga-DOTATATE Uptake in an Endolymphatic Sac Tumor: Radiologic-Pathologic Correlation

Clin Nucl Med. 2020 Jul;45(7):563-565. doi: 10.1097/RLU.0000000000003092.

Abstract

After dedicated CT and MRI, Ga-DOTATATE PET/CT was performed in a patient with a temporal bone mass with primary diagnostic considerations of an endolymphatic sac tumor versus a glomus jugulotympanicum paraganglioma. The Ga-DOTATATE PET showed mild radiotracer uptake in the mass (SUVmax, 10.9). After surgical resection, pathology revealed an endolymphatic sac tumor. Immunohistochemical staining demonstrated somatostatin receptor type 2A expression in the vasculature of the mass, but not in the tumor cells.

MeSH terms

  • Adult
  • Aged
  • Diagnosis, Differential
  • Ear Neoplasms / diagnostic imaging*
  • Ear Neoplasms / metabolism
  • Ear Neoplasms / pathology*
  • Endolymphatic Sac / diagnostic imaging*
  • Endolymphatic Sac / metabolism
  • Endolymphatic Sac / pathology*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Organometallic Compounds / metabolism*
  • Paraganglioma / diagnosis
  • Positron Emission Tomography Computed Tomography*
  • Receptors, Somatostatin / metabolism

Substances

  • Organometallic Compounds
  • Receptors, Somatostatin
  • gallium Ga 68 dotatate
  • somatostatin receptor 2