Linking Dietary Exposure to 1,2-Dehydropyrrolizidine Alkaloids with Cancers and Chemotherapy-Induced Pulmonary and Hepatic Veno-Occlusive Diseases

J Agric Food Chem. 2020 Jun 3;68(22):5995-5997. doi: 10.1021/acs.jafc.0c02582. Epub 2020 May 20.

Authors

John A Edgar¹, Russell J Molyneux², Steven M Colegate³

Affiliations

¹ CSIRO Agriculture and Food, 11 Julius Avenue, North Ryde, New South Wales 2113, Australia.
² Daniel K. Inouye College of Pharmacy, University of Hawai'i at Hilo, 200 West Kawili Street, Hilo, Hawaii 96720-4091, United States.
³ Poisonous Plant Research Laboratory, United States Department of Agriculture (USDA), 1150 East 1400 North, Logan, Utah 84341, United States.

PMID: 32432873
DOI: 10.1021/acs.jafc.0c02582

No abstract available

MeSH terms

Animals
Dietary Exposure / adverse effects*
Food Contamination / analysis
Hepatic Veno-Occlusive Disease / etiology*
Hepatic Veno-Occlusive Disease / metabolism
Humans
Livestock / metabolism
Neoplasms / etiology*
Neoplasms / metabolism
Pyrrolizidine Alkaloids / chemistry
Pyrrolizidine Alkaloids / metabolism*
Pyrrolizidine Alkaloids / toxicity*

Substances

Pyrrolizidine Alkaloids