Triterpenoids From Alisma Species: Phytochemistry, Structure Modification, and Bioactivities

Pengli Wang; Tongxin Song; Rui Shi; Mingshuai He; Rongrong Wang; Jialin Lv; Miaomiao Jiang

doi:10.3389/fchem.2020.00363

Triterpenoids From Alisma Species: Phytochemistry, Structure Modification, and Bioactivities

Front Chem. 2020 Apr 30:8:363. doi: 10.3389/fchem.2020.00363. eCollection 2020.

Authors

Pengli Wang¹, Tongxin Song¹, Rui Shi¹, Mingshuai He¹, Rongrong Wang¹, Jialin Lv¹, Miaomiao Jiang¹

Affiliation

¹ Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Abstract

Plants from Alisma species belong to the genus of Alisma Linn. in Alismataceae family. The tubers of A. orientale (Sam.) Juzep, also known as Ze Xie in Chinese and Takusha in Japanese, have been used in traditional medicine for a long history. Triterpenoids are the main secondary metabolites isolated from Alisma species, and reported with various bioactive properties, including anticancer, lipid-regulating, anti-inflammatory, antibacterial, antiviral and diuretic activities. In this brief review, we aimed to summarize the phytochemical and pharmacological characteristics of triterpenoids found in Alisma, and discuss their structure modification to enhance cytotoxicity as well.

Keywords: Alisma; anticancer; lipid-regulation; structure; triterpenoids.

Publication types

Review