The data concerning 2500 allergic patients are analysed and the low incidence of so-called "minor pollens" in respiratory allergopathies is documented. Moreover a frequent association of positivity with the so-called "major allergens" (Grass, Parietaria, Dermatophagoides) was observed. Specific hyposensitizing therapy is advised only in carefully selected patients, those showing perfect agreement between allergological data and clinical symptomatology.