Lung abscess secondary to lung cancer with Eikenella corrodens and Streptococcus anginosus: a case report

BMC Infect Dis. 2020 May 18;20(1):351. doi: 10.1186/s12879-020-05054-y.

Abstract

Background: Eikenella corrodens and Streptococcus anginosus, which are primary colonization bacteria of the normal flora of the oropharynx, are infrequent bacteria, especially the former. Here, we report a case of lung abscess with a coinfection of Eikenella corrodens and Streptococcus anginosus in a lung cancer patient.

Case presentation: A 66-year-old Chinese man with lung cancer was admitted to the hospital, complaining of a cough and expectoration for five months and fever for two months. After a series of inspections to differentiate a cancer-related fever from an infectious fever, he was diagnosed with lung abscess. Draining pus culture demonstrated Eikenella corrodens and Streptococcus anginosus. After more than 1 month of antibiotic therapy and draining in total, he gradually recovered to fight against lung cancer.

Conclusion: This report highlights the increased pathogenicity of Eikenella corrodens and Streptococcus anginosus in an immunocompromised cancer patient, especially after a few invasive operations. Additionally, even though a patient has been diagnosed with cancerous fever, strong vigilance is needed in case an infection arises.

Keywords: Case report; Eikenella corrodens; Lung abscess; Lung cancer; Streptococcus anginosus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Coinfection / diagnosis*
  • Coinfection / drug therapy
  • Drainage
  • Eikenella corrodens / isolation & purification*
  • Fever / drug therapy
  • Gram-Negative Bacterial Infections / diagnosis*
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Lung Abscess / drug therapy
  • Lung Abscess / microbiology*
  • Lung Neoplasms / complications*
  • Male
  • Streptococcal Infections / diagnosis*
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / microbiology
  • Streptococcus anginosus / isolation & purification*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents