Amyloid nodule and primary pulmonary lymphoma in the same lung: Radiologic-pathologic correlation of a rare combination

Andrei Jipa; Jonathan Glaab

doi:10.1016/j.radcr.2020.04.016

Amyloid nodule and primary pulmonary lymphoma in the same lung: Radiologic-pathologic correlation of a rare combination

Radiol Case Rep. 2020 May 7;15(7):933-938. doi: 10.1016/j.radcr.2020.04.016. eCollection 2020 Jul.

Authors

Andrei Jipa¹, Jonathan Glaab²

Affiliations

¹ Radiology Resident, MetroHealth Medical Center and Case Western Reserve School of Medicine, Cleveland, OH, USA.
² Department of Radiology, MetroHealth Medical Center and Case Western Reserve School of Medicine, Cleveland, OH, USA.

Abstract

A 61-year-old man presented for lung cancer screening with low dose CT. A spiculated right apical nodule suspicious for primary lung malignancy and an indeterminate small basilar consolidation were identified. PET/CT was notable for increased FDG uptake in the basilar consolidation. Transthoracic needle biopsy of both lesions was performed which lead to pathologic diagnoses of pulmonary amyloid nodule for the apical nodule and pulmonary extramarginal zone lymphoma of the mucosa associate lymphoid tissue for the basilar consolidation. While incidental findings are common in lung cancer screening CT, exceedingly rare diagnoses or combinations or diagnoses may also be encountered. This case also underscores the value of pathologic diagnosis in cases of indeterminate lung nodules.

Keywords: Amyloid lung nodule; Lung cancer screening; Pulmonary lymphoma; Pulmonary nodule.

Publication types

Case Reports