Borderline ovarian tumours: management in the era of fertility-sparing surgery

Mattia Maramai; Fabio Barra; Mario Valenzano Menada; Sara Stigliani; Melita Moioli; Sergio Costantini; Simone Ferrero

doi:10.3332/ecancer.2020.1031

Borderline ovarian tumours: management in the era of fertility-sparing surgery

Ecancermedicalscience. 2020 May 6:14:1031. doi: 10.3332/ecancer.2020.1031. eCollection 2020.

Authors

Mattia Maramai^{1

2}, Fabio Barra^{1

2}, Mario Valenzano Menada^{1

2}, Sara Stigliani^{1

2}, Melita Moioli², Sergio Costantini^{1

2}, Simone Ferrero^{1

2}

Affiliations

¹ Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, Italy.
² Academic Unit of Obstetrics and Gynaecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

Abstract

Borderline ovarian tumours (BOTs) are ovarian neoplasms characterised by epithelial proliferation, variable nuclear atypia and no evidence of destructive stromal invasion. BOTs account for approximately 15% of all epithelial ovarian cancers. Due to the fact that the majority of BOTs occur in women under 40 years of age, their surgical management often has to consider fertility-sparing approaches. The aim of this mini-review is to discuss the state of the art of fertility-sparing surgery for BOTs with a specific focus on the extent of surgery, post-operative management and fertility.

Keywords: fertility preservation; ovarian cysts; ovarian neoplasms; salpingo-oophorectomy.

Publication types

Review