Fulminant Tracheobronchial Aspergillosis in an Apparently Healthy Adult

Intern Med. 2020;59(10):1295-1298. doi: 10.2169/internalmedicine.3857-19. Epub 2020 May 15.

Abstract

A 56-year-old healthy man who was a current smoker died from fulminant tracheobronchial aspergillosis despite a month of treatment with a combination of intravenous anti-fungal agents that had been started immediately after the diagnosis. This case report is important for understanding and managing fulminant Aspergillus infections in healthy subjects, although the pathogenesis and underlying pathways are still unknown.

Keywords: fulminant; healthy individual; tracheobronchial aspergillosis.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Aspergillosis / diagnosis
  • Aspergillosis / drug therapy*
  • Bronchitis / drug therapy*
  • Bronchitis / microbiology*
  • Fatal Outcome
  • Humans
  • Male
  • Middle Aged
  • Tracheitis / drug therapy*
  • Tracheitis / microbiology*

Substances

  • Antifungal Agents