Intramedullary spinal nephroblastoma in a mixed breed dog

J Vet Med Sci. 2020 Jul 10;82(7):917-921. doi: 10.1292/jvms.20-0068. Epub 2020 May 18.

Abstract

A 1-year-old male mixed breed dog presented for the evaluation of progressive hindlimb paresis. Neurological examination indicated a spinal cord lesion between the 3rd thoracic and 3rd lumbar vertebrae. Magnetic resonance imaging (MRI) revealed an intramedullary spinal cord lesion located at the level of the 1st and 2nd lumbar vertebrae. Following cytoreductive surgery of the mass, palliative radiation therapy was administered. A diagnosis of nephroblastoma was made based on histological examination. After radiation therapy, the disappearance of the spinal lesion was confirmed by MRI. The dog was improved from gait abnormality and alive at 16 months postoperatively, with slight signs of neurological dysfunction.

Keywords: dog; intramedullary; radiation therapy; spinal nephroblastoma.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Dog Diseases / diagnostic imaging
  • Dog Diseases / radiotherapy
  • Dog Diseases / surgery*
  • Dogs
  • Magnetic Resonance Imaging / veterinary
  • Male
  • Paresis / etiology
  • Paresis / veterinary
  • Spinal Cord Neoplasms / diagnostic imaging
  • Spinal Cord Neoplasms / radiotherapy
  • Spinal Cord Neoplasms / surgery
  • Spinal Cord Neoplasms / veterinary*
  • Wilms Tumor / diagnostic imaging
  • Wilms Tumor / radiotherapy
  • Wilms Tumor / surgery
  • Wilms Tumor / veterinary*