Cell Membrane Coated-Biomimetic Nanoplatforms Toward Cancer Theranostics

Tingting Li; Xiang Qin; Yichao Li; Xue Shen; Shun Li; Hong Yang; Chunhui Wu; Chuan Zheng; Jie Zhu; Fengming You; Yiyao Liu

doi:10.3389/fbioe.2020.00371

Cell Membrane Coated-Biomimetic Nanoplatforms Toward Cancer Theranostics

Front Bioeng Biotechnol. 2020 Apr 29:8:371. doi: 10.3389/fbioe.2020.00371. eCollection 2020.

Authors

Tingting Li^{1

2}, Xiang Qin^{1

2}, Yichao Li¹, Xue Shen³, Shun Li^{1

2}, Hong Yang^{1

2}, Chunhui Wu^{1

2}, Chuan Zheng⁴, Jie Zhu⁴, Fengming You⁴, Yiyao Liu^{1

4}

Affiliations

¹ Department of Biophysics, School of Life Sciences and Technology, University of Electronic Science and Technology of China, Chengdu, China.
² Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu, China.
³ Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu, China.
⁴ Department of Cancer Research, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Abstract

Research of nanotechnology for cancer therapy and diagnosis extends beyond drug delivery into the targeted site or surveillance the distribution of nanodrugs in vivo or distinction tumor tissue from normal tissue. To satisfy the clinic needs, nanotheranostic platform should hide the surveillance by immune system and the sequestration by filtration organs (i.e., liver and spleen). Use of biologically derived cellular components in the fabrication of nanoparticles can hide these barriers. In this review, we update the recent progress on cell membrane-coated nanoparticles for cancer theranostics. We hope this review paper can inspire further innovations in biomimetic nanomedicine.

Keywords: biomimetic; cancer; cell membrane; nanocomplex; theranostic.

Publication types

Review