Outcome of idiopathic intracranial hypertension after laparoscopic sleeve gastrectomy

Surg Obes Relat Dis. 2020 Sep;16(9):1195-1201. doi: 10.1016/j.soard.2020.03.032. Epub 2020 Apr 11.

Abstract

Background: Idiopathic intracranial hypertension (IIH) predominantly affects young, obese women and presents with signs and symptoms of increased intracranial pressure, such as headaches and visual impairment.

Objective: We aim to present our experience in the management of IIH.

Setting: University Hospital.

Methods: Obese IIH patients who had a laparoscopic sleeve gastrectomy during the study period (2 years) were included. Data were retrieved from prospectively collected database. Headaches, visual alterations, and medications or interventions used to treat are discussed.

Results: The study included 16 obese women with IIH. Mean age was 31 ± 2 years (range, 25-44 yr) and mean body mass index was 46 ± 4 kg/m2 (range, 42-53 kg/m2). Main symptoms and signs were chronic headaches (14), impaired vision (15), vision loss (1), papilledema (6), and field defects in 4 patients. Symptoms were present for a mean of 5 years (4-11). History of medical treatment with carbonic anhydrase inhibitor (acetazolamide) and thecoperitoneal shunting was present in 12 and 9 patients, respectively. Mean lumbar puncture opening pressure was 41.2 ± 21- (range, 30-64) cm water. At 12 months after laparoscopic sleeve gastrectomy, body mass index and percentage excess weight loss were 27.8 ± 1 kg/m2 and 75.2 ± 2%, respectively. Symptoms gradually improved with complete resolution in all but 2 patients (87.5%).

Conclusion: The present work emphasizes the role of bariatric surgery in the management of obese patients with IIH. Larger, prospective, controlled studies are needed.

Keywords: Headaches; Idiopathic intracranial hypertension (IIH); Laparoscopic sleeve gastrectomy (LSG); Obesity; Papilledema; Visual defects.

MeSH terms

  • Adult
  • Body Mass Index
  • Female
  • Gastrectomy
  • Humans
  • Laparoscopy*
  • Obesity, Morbid* / surgery
  • Prospective Studies
  • Pseudotumor Cerebri* / surgery
  • Retrospective Studies
  • Treatment Outcome
  • Weight Loss