The biodegradable material poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) scaffold has good biodegradability, but poor biocompatibility limits its application in the biological field. And it can effectively improve its biological activity by compounding with the bone conduction activity material of Barium titanate (BT). The PHBV and piezoelectric material BT were prepared into porous composite scaffolds with porosity of 45-50%. The mechanical properties and electrical properties of BT/PHBV scaffolds were systematically studied. The results showed that the piezoelectric coefficient d33 was 0.2-1.5 pC/N. Moreover, the compressive strength and elastic modulus were 1.0-2.0 MPa and 100-200 MPa, respectively. The results of degradation and mineralization showed that BT/PHBV scaffolds had good degradation and mineralization performance which was indicated that the materials had good biological activity.
Keywords: BT/PHBV; biological activity; electrical property; mechanical property; porous composite scaffold.