The pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses

Hum Vaccin Immunother. 2020 Oct 2;16(10):2373. doi: 10.1080/21645515.2020.1758534. Epub 2020 May 13.

Abstract

We are proposing the use of pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. The designed strategy represents a potential treatment to reduce the overall viral load in the lungs and to help the immune system to successfully stave off the infection.

Keywords: Coronavirus; SARS-COV-2; liposome.

MeSH terms

  • Angiotensin-Converting Enzyme 2
  • Betacoronavirus
  • COVID-19
  • Cell Membrane / metabolism
  • Coronavirus Infections / prevention & control*
  • Membranes, Artificial*
  • Pandemics / prevention & control*
  • Peptidyl-Dipeptidase A / metabolism*
  • Pneumonia, Viral / prevention & control*
  • Proteolipids / metabolism*
  • SARS-CoV-2
  • Spike Glycoprotein, Coronavirus / metabolism*
  • Viral Load

Substances

  • Membranes, Artificial
  • Proteolipids
  • Spike Glycoprotein, Coronavirus
  • proteoliposomes
  • spike protein, SARS-CoV-2
  • Peptidyl-Dipeptidase A
  • Angiotensin-Converting Enzyme 2