Colesevelam in the management of type 2 diabetes

J Pak Med Assoc. 2020 May;70(5):934-936.

Abstract

Colesevelam is a bile acid sequestrant, approved for the management of both dyslipidaemia and type 2 diabetes. This review discusses the potential for the use of colesevelam in the management of type 2 diabetes. Expert opinion suggests possible indications where colesevelam may add value as a glucose lowering agent. It also highlights the limitations of the drug, and precautions that must be observed while using it.

Keywords: bile acid sequestrant, colesevelam, GLP1RA, LDL cholesterol, lipocrinology, type 2 diabetes.

Publication types

  • Review

MeSH terms

  • Anticholesteremic Agents / pharmacology
  • Colesevelam Hydrochloride / pharmacology*
  • Diabetes Mellitus, Type 2* / drug therapy
  • Diabetes Mellitus, Type 2* / metabolism
  • Dyslipidemias / drug therapy*
  • Dyslipidemias / metabolism
  • Humans
  • Pharmacovigilance

Substances

  • Anticholesteremic Agents
  • Colesevelam Hydrochloride