Current Progress in Biomedical Applications of Chitosan-Carbon Nanotube Nanocomposites: A Review

Mini Rev Med Chem. 2020;20(16):1619-1632. doi: 10.2174/1389557520666200513120407.

Abstract

The currently observed development of medical science results from the constant search for innovative solutions to improve the health and quality of life of patients. Particular attention is focused on the design of a new generation of materials with a high degree of biocompatibility and tolerance towards the immune system. In addition, apart from biotolerance, it is important to ensure appropriate mechanical and technological properties of materials intended for intra-body applications. Knowledge of the above parameters becomes the basis for considerations related to the possibilities of choosing the appropriate polymer materials. The researchers' interest, as evidenced by the number of available publications, is attracted by nanobiocomposites based on chitosan and carbon nanotubes, which, due to their properties, enable integration with the tissues of the human body. Nanosystems can be used in many areas of medicine. They constitute an excellent base for use as dressing materials, as they exhibit antimicrobial properties. In addition, they can be carriers of drugs and biological macromolecules and can be used in gene therapy, tissue engineering, and construction of biosensors. For this reason, potential application areas of chitosan-carbon nanotube nanocomposites in medical sciences are presented in this publication, considering the characteristics of the system components.

Keywords: Nanotechnology; biopolymers; carbon nanotubes; chitin; chitosan; nano-biocomposites; nanomedicine.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry*
  • Biomedical Research*
  • Biosensing Techniques
  • Chitosan / chemistry*
  • Nanocomposites / chemistry*
  • Nanotubes, Carbon / chemistry*
  • Tissue Engineering

Substances

  • Biocompatible Materials
  • Nanotubes, Carbon
  • Chitosan