Optical Identification of Middle Ear Infection

Molecules. 2020 May 9;25(9):2239. doi: 10.3390/molecules25092239.

Abstract

Ear infection is one of the most commonly occurring inflammation diseases in the world, especially for children. Almost every child encounters at least one episode of ear infection before he/she reaches the age of seven. The typical treatment currently followed by physicians is visual inspection and antibiotic prescription. In most cases, a lack of improper treatment results in severe bacterial infection. Therefore, it is necessary to design and explore advanced practices for effective diagnosis. In this review paper, we present the various types of ear infection and the related pathogens responsible for middle ear infection. We outline the conventional techniques along with clinical trials using those techniques to detect ear infections. Further, we highlight the need for emerging techniques to reduce ear infection complications. Finally, we emphasize the utility of Raman spectroscopy as a prospective non-invasive technique for the identification of middle ear infection.

Keywords: Raman spectroscopy; bacterial infection; drug-resistant microbial; label-free method; middle ear infection; otitis media; otoscope.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / diagnostic imaging*
  • Bacterial Infections / drug therapy
  • Clinical Trials as Topic
  • Female
  • Humans
  • Male
  • Microscopy, Confocal
  • Optical Imaging / methods*
  • Otitis Media / diagnostic imaging
  • Otitis Media / drug therapy
  • Otitis Media / microbiology*
  • Prospective Studies
  • Sensitivity and Specificity
  • Spectrum Analysis, Raman

Substances

  • Anti-Bacterial Agents