Paraneoplastic encephalitis with leukoencephalopathy in primary fallopian tube carcinoma

Austin Shinagawa; Nephtali Barrera; Michael Taylor; Natasa Dragicevic

doi:10.1016/j.radcr.2020.04.013

Paraneoplastic encephalitis with leukoencephalopathy in primary fallopian tube carcinoma

Radiol Case Rep. 2020 May 4;15(7):904-907. doi: 10.1016/j.radcr.2020.04.013. eCollection 2020 Jul.

Authors

Austin Shinagawa¹, Nephtali Barrera¹, Michael Taylor¹, Natasa Dragicevic²

Affiliations

¹ University of Nevada, Reno School of Medicine. 1664 N. Virginia Street, Reno, NV 89557, USA.
² Renown Regional Medical Center, Department of Neurology, Reno, NV 89502.

Abstract

Previous reports of paraneoplastic encephalitis occurring in primary fallopian tube carcinoma have been exclusively classified as paraneoplastic cerebellar degeneration, with MR imaging either unremarkable or demonstrating cerebellar atrophy. We report a case of paraneoplastic encephalitis in a 64-year-old female with primary fallopian tube carcinoma, reminiscent of N-methyl d-aspartate receptor encephalitis, with MR imaging demonstrating bilateral subcortical and deep white matter T2-FLAIR hyperintensities sparing cerebellar and brainstem structures. To our knowledge, this represents the first reported case of noncerebellar paraneoplastic encephalitis related to primary fallopian tube carcinoma.

Keywords: Encephalitis; Leukoencephalopathy; NMDA; Paraneoplastic; Primary fallopian tube carcinoma.

Publication types

Case Reports