An Effective Convolutional Neural Network for Classifying Red Blood Cells in Malaria Diseases

Interdiscip Sci. 2020 Jun;12(2):217-225. doi: 10.1007/s12539-020-00367-7. Epub 2020 May 11.

Abstract

Malaria is one of the epidemics that can cause human death. Accurate and rapid diagnosis of malaria is important for treatment. Due to the limited number of data and human factors, the prediction performance and reliability of traditional classification methods are often affected. In this study, we propose an efficient and novel classification network named Attentive Dense Circular Net (ADCN) which based on Convolutional Neural Networks (CNN). The ADCN is inspired by the ideas of residual and dense networks and combines with the attention mechanism. We train and evaluate our proposed model on a publicly available red blood cells (RBC) dataset and compare ADCN with several well-established CNN models. Compared to other best performing CNN model in our experiments, ADCN shows superiority in all performance criteria such as accuracy (97.47% vs 94.61%), sensitivity (97.86% vs 95.20%) and specificity (97.07% vs 92.87%). Finally, we discuss the obtained results and analyze the difficulties of RBCs classification.

Keywords: Classification; Convolutional neural networks; Malaria; Red blood cell.

Publication types

  • Evaluation Study
  • Validation Study

MeSH terms

  • Deep Learning
  • Erythrocytes / classification
  • Erythrocytes / parasitology*
  • Humans
  • Malaria / blood
  • Malaria / diagnosis*
  • Malaria / parasitology
  • Models, Biological*
  • Neural Networks, Computer*
  • Plasmodium / growth & development*
  • Reproducibility of Results