Defense Peptides From the α-Hairpinin Family Are Components of Plant Innate Immunity

Anna A Slavokhotova; Eugene A Rogozhin

doi:10.3389/fpls.2020.00465

Defense Peptides From the α-Hairpinin Family Are Components of Plant Innate Immunity

Front Plant Sci. 2020 Apr 23:11:465. doi: 10.3389/fpls.2020.00465. eCollection 2020.

Authors

Anna A Slavokhotova^{1

2}, Eugene A Rogozhin^{1

3

4}

Affiliations

¹ M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
² Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Moscow, Russia.
³ All-Russian Institute of Plant Protection, St. Petersburg-Pushkin, Russia.
⁴ Gause Institute of New Antibiotics, Moscow, Russia.

Abstract

Plant immunity represents a sophisticated system, including both basal and inducible mechanisms, to prevent pathogen infection. Antimicrobial peptides (AMPs) are among the innate immunity components playing a key role in effective and rapid response against various pathogens. This review is devoted to a small family of defense peptides called α-hairpinins. The general characters of the family, as well as the individual features of each member, including biological activities, structures of precursor proteins, and spatial structures, are described. Possible applications of α-hairpinin peptides in drug design are discussed.

Keywords: antimicrobial peptides; defense peptides; plant innate immunity; primary and spatial structures; protein-precursors; α-hairpinins.

Publication types

Review