Sinonasal Teratocarcinosarcoma, a Rare Tumor Involving Both the Nasal Cavity and the Cranial Cavity

Sang Youl Yoon; Ki Su Park; Jeong Hyun Hwang; Seong Hyun Park; Man Hoon Han

doi:10.14791/btrt.2020.8.e2

Sinonasal Teratocarcinosarcoma, a Rare Tumor Involving Both the Nasal Cavity and the Cranial Cavity

Brain Tumor Res Treat. 2020 Apr;8(1):57-61. doi: 10.14791/btrt.2020.8.e2.

Authors

Sang Youl Yoon¹, Ki Su Park², Jeong Hyun Hwang³, Seong Hyun Park¹, Man Hoon Han⁴

Affiliations

¹ Department of Neurosurgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.
² Department of Neurosurgery, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, Korea.
³ Department of Neurosurgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea. jhwang@knu.ac.kr.
⁴ Department of Pathology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.

Abstract

Sinonasal teratocarcinosarcoma (SNTCS), a very rare tumor, is known to be a heterogeneous with epithelial, mesenchymal, and neuroepithelial components and shows a very aggressive clinical course. Due to the heterogeneity of this tumor, it is often misdiagnosed. No definitive treatment modality has been reported because it is a very rare tumor. A 44-year-old man presented to a rhinologist with headache and nasal obstruction, and an intranasal tumor was found that invaded into the cranial cavity. He underwent combined surgery with a rhinologist and a neurosurgeon following cognitive decline that worsened after a transnasal biopsy. The patient was diagnosed with SNTCS and underwent radiotherapy. However, residual tumor was found during radiotherapy and additional chemotherapy was administered. Follow-up brain MRI revealed no remnant or recurrent lesion. SNTCS is a tumor that has not yet been well researched and should be further investigated for proper treatment.

Keywords: Brain tumor; Chemotherapy; Radiotherapy; Teratocarcinosarcoma.

Publication types

Case Reports