HPV condylomatosis region treated with multiple sessions of MAL-PDT: A case report

Photodiagnosis Photodyn Ther. 2020 Sep:31:101812. doi: 10.1016/j.pdpdt.2020.101812. Epub 2020 May 7.

Abstract

Condyloma or genital warts affect the tissues of the genital area due to infections induced by Human papillomavirus. There are some topical therapies indicated for condyloma lesions treatment but all of them present a high rate of recurrence. Photodynamic Therapy is proving to be an interesting strategy for treating these lesions, capable also to treat virus-infected cells on subclinical lesions. A patient with a significative condylomatosis region was treated with six MAL-PDT sessions. Due to its large thickness, other topical procedures probably would have low effectiveness. After the treatment, the tissue presented clinical absence of lesion and no apparent scar, with good aesthetic result and preserving the sensitivity of the region and a follow up of eleven months without recurrence.

Keywords: Condyloma; Genital warts; HPV; Photochemotherapy; Topical Photodynamic Therapy.

Publication types

  • Case Reports

MeSH terms

  • Aminolevulinic Acid / therapeutic use
  • Humans
  • Papillomavirus Infections* / drug therapy
  • Photochemotherapy* / methods
  • Photosensitizing Agents / therapeutic use

Substances

  • Photosensitizing Agents
  • Aminolevulinic Acid