Although continuous outbreak of coronavirus disease 2019, it has been widely reported, there were few reports regarding family cases. We reported a group of family cluster outbreak cases confirmed in Xiangya Hospital, Central South University, China, and their clinical and image characteristics have been analyzed in order to provide reference for the prevention and early diagnosis of this disease. A total of 5 patients from one family, including 4 adults and 1 child, had a history of human contact in Wuhan, Hubei. Four adult patients showed different symptoms, including cough, fever, pharyngeal pain, and dyspnea, while the child patient had no symptoms. Laboratory examination showed no abnormality in all the patients except for slight increase in CRP in 2 patients and mild abnormal liver function index in 1 patient. The chest CT showed that all patients had abnormal images, with different degrees of manifestations.All patients were finally diagnosed by the nucleic acid test.
随着2019冠状病毒病疫情的持续，已有多篇文献对该病进行了报道，但对家族暴发的2019冠状病毒病的报道较少。现报告一组中南大学湘雅医院确诊的2019冠状病毒病家族聚集暴发病例，分析其临床及影像学特点，以期为该病的防控及诊断提供参考。患者共5例，皆来自同一家族，均有与湖北武汉人员接触史，其中4例为成人，1例为儿童。4例成人患者症状不一，表现为咳嗽、发热、咽痛、呼吸困难，儿童患者无症状。实验室检查除2例患者CRP稍增高，1例患者肝功能指标轻度异常外，其他患者均未见异常。患者胸部CT检查结果均有异常，但影像学表现及严重程度不一。患者最终均行核酸检测确诊。.
Keywords: coronavirus disease 2019; crazy-paving sign; ground-glass opacity; halo sign.