Lemon seed allergy: a case presentation

O Stephanie Kayode; Nuevalynne Prado; David J Thursfield; Stephen J Till; Leonard Q C Siew

doi:10.1186/s13223-020-00429-x

Lemon seed allergy: a case presentation

Allergy Asthma Clin Immunol. 2020 Apr 29:16:32. doi: 10.1186/s13223-020-00429-x. eCollection 2020.

Authors

O Stephanie Kayode¹, Nuevalynne Prado¹, David J Thursfield¹, Stephen J Till^{1

2}, Leonard Q C Siew^{1

2}

Affiliations

¹ 1Department of Adult Allergy, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT UK.
² 2Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.

Abstract

Background: We report a case of IgE-mediated hypersensitivity to lemon seed. We demonstrate for the first time a pattern of cross-sensitisation between seeds of citrus hybrid species from similar ancestral species origins.

Case report: Described is a case of a 26-year-old female with recurrent anaphylaxis on exposure to lemon seed with sensitisation shown on prick to prick testing. Prick to prick testing was also performed to a variety of citrus fruit seeds and edible foods from additional notable families of the Sapindale order.

Conclusion: In cases of unexplained or recurrent anaphylaxis in adult patients, citrus seed allergy should be considered.

Keywords: Adult; Anaphylaxis; Case report; Citrus; Food hypersensitivity; Hybridisation; Immunoglobulin E; Seed; Tree Nut.

Publication types

Case Reports