Validation of Malnutrition Screening Tools in Liver Cirrhosis

Nutrients. 2020 May 3;12(5):1306. doi: 10.3390/nu12051306.

Abstract

Malnutrition in liver cirrhosis is frequently underestimated. To determine if a patient is at risk of malnutrition, several screening tools have been established. However, most of them are not validated for patients with liver cirrhosis. Therefore, we compared the RFH-NPT (Royal Free Hospital Nutritional Prioritizing Tool) as the validated gold standard for malnutrition screening in cirrhosis patients with GMS (Graz Malnutrition Screening), NRS-2002 (Nutritional Risk Screening) and MNA-SF (Mini Nutritional Assessment-Short Form). Based on common validity criteria for screening tools, only the MNA-SF showed fair correlation (12/15 points) with the RFH-NPT, whereas NRS-2002 and GMS performed worse (6/15 points). Taken together, our results suggest that NRS-2002 and GMS are not suitable for screening of malnutrition in cirrhosis patients. A cirrhosis-specific screening tool like RFH-NPT should be used to assess malnutrition and to identify those at risk of malnutrition.

Keywords: assessment; liver cirrhosis; malnutrition; screening.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Liver Cirrhosis / complications*
  • Male
  • Malnutrition / diagnosis*
  • Malnutrition / etiology
  • Mass Screening / methods*
  • Middle Aged
  • Nutrition Assessment*
  • Prospective Studies
  • Risk
  • Risk Assessment
  • Young Adult