Potential Applications of Plant Biotechnology against SARS-CoV-2

Trends Plant Sci. 2020 Jul;25(7):635-643. doi: 10.1016/j.tplants.2020.04.009. Epub 2020 Apr 24.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus responsible for an ongoing human pandemic (COVID-19). There is a massive international effort underway to develop diagnostic reagents, vaccines, and antiviral drugs in a bid to slow down the spread of the disease and save lives. One part of that international effort involves the research community working with plants, bringing researchers from all over the world together with commercial enterprises to achieve the rapid supply of protein antigens and antibodies for diagnostic kits, and scalable production systems for the emergency manufacturing of vaccines and antiviral drugs. Here, we look at some of the ways in which plants can and are being used in the fight against COVID-19.

Keywords: COVID-19; molecular farming; pandemic; transgenic plants; transient expression; virus-like particles.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiviral Agents
  • Betacoronavirus
  • Biotechnology
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Coronavirus Infections* / diagnosis
  • Humans
  • Pandemics
  • Plants*
  • Pneumonia, Viral
  • SARS-CoV-2
  • Severe acute respiratory syndrome-related coronavirus*

Substances

  • Antiviral Agents