Disagreement between guidelines regarding the third step of asthma drug therapy for school-age children

Allergol Immunopathol (Madr). 2020 Nov-Dec;48(6):789-791. doi: 10.1016/j.aller.2019.12.004. Epub 2020 May 4.

Abstract

With the help of a routine clinical case, we highlighted the difference between two of the best asthma guidelines available at the time regarding therapeutic suggestions for the so-called "third step" for school-age asthmatic children. We have analyzed the scientific evidence that each of the two guidelines brings to support their position. Finally, we have motivatedly solved the clinical scenario. However, the question of disagreement between two guidelines remains unresolved. This can lead to unjustified differences in the management of schoolchildren with persistent asthma.

Keywords: Asthma guidelines; Inhaled corticosteroid; Leukotriene receptor antagonist; Long-acting β2 agonist; School-age children.

MeSH terms

  • Administration, Inhalation
  • Adrenergic beta-2 Receptor Agonists / administration & dosage
  • Age Factors
  • Anti-Asthmatic Agents / administration & dosage*
  • Asthma / drug therapy*
  • Child
  • Drug Therapy, Combination / methods
  • Drug Therapy, Combination / standards
  • Evidence-Based Medicine / methods
  • Evidence-Based Medicine / standards*
  • Glucocorticoids / administration & dosage
  • Humans
  • Leukotriene Antagonists / administration & dosage
  • Male
  • Practice Guidelines as Topic / standards*
  • Treatment Outcome

Substances

  • Adrenergic beta-2 Receptor Agonists
  • Anti-Asthmatic Agents
  • Glucocorticoids
  • Leukotriene Antagonists