A photoelectrochemical aptasensor for the sensitive detection of streptomycin based on a TiO2/BiOI/BiOBr heterostructure

Yanni Luo; Xuecai Tan; David J Young; Quanyou Chen; Yuehui Huang; Defen Feng; Chenhao Ai; Yan Mi

doi:10.1016/j.aca.2020.04.021

A photoelectrochemical aptasensor for the sensitive detection of streptomycin based on a TiO₂/BiOI/BiOBr heterostructure

Anal Chim Acta. 2020 Jun 8:1115:33-40. doi: 10.1016/j.aca.2020.04.021. Epub 2020 Apr 13.

Authors

Yanni Luo¹, Xuecai Tan², David J Young³, Quanyou Chen¹, Yuehui Huang¹, Defen Feng¹, Chenhao Ai¹, Yan Mi¹

Affiliations

¹ School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Key Laboratory of Guangxi Colleges and Universities for Food Safety and Pharmaceutical Analytical Chemistry, Nanning, 530008, PR China.
² School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Key Laboratory of Guangxi Colleges and Universities for Food Safety and Pharmaceutical Analytical Chemistry, Nanning, 530008, PR China. Electronic address: gxunxctan@126.com.
³ College of Engineering, Information Technology and Environment, Charles Darwin University, Darwin, NT, 0909, Australia.

PMID: 32370867
DOI: 10.1016/j.aca.2020.04.021

Abstract

In photoelectrochemical sensor (PEC sensor), sensitivity and selectivity are two essential factors which are determined by photosensitive of materials and identification of elements. Herein, a novel PEC aptamer sensor for streptomycin-specific detection was developed, with which the visible-light-active TiO₂/BiOI/BiOBr heterostructure and aptamers were employed as photoactive material and bio-identification elements, separately. The combination of an appropriate amount of TiO₂ with BiOI/BiOBr enhanced the photocurrent response, and thus is beneficial to the construction of PEC sensors. In addition, the one-pot synthesis of TiO₂/BiOI/BiOBr has the advantage of being environmentally-friendly. Under optimized conditions, the photocurrent response of aptamer/TiO₂/BiOI/BiOBr/ITO is linear with SRT concentration from 0.05 to 150 nM, and the detection limit (S/N = 3) is as low as 0.04 nM. This novel PEC sensing strategy provided an ultra-sensitive sensor with high selectivity and stability for SRT detection.

Keywords: Photoelectrochemical aptasensor; Streptomycin; TiO(2)/BiOI/BiOBr.

MeSH terms

Aptamers, Nucleotide / chemistry*
Biosensing Techniques
Bismuth / chemistry*
Electrochemical Techniques*
Molecular Structure
Photochemical Processes
Streptomycin / analysis*
Titanium / chemistry*

Substances

Aptamers, Nucleotide
titanium dioxide
Titanium
bismuth oxybromide
Bismuth
Streptomycin