Feasibility of performance-based functional assessment in brain tumour survivors

Eur J Cancer Care (Engl). 2020 Jul;29(4):e13238. doi: 10.1111/ecc.13238. Epub 2020 May 5.

Abstract

Introduction: Rehabilitation and exercise interventions are beneficial for the physical and psychological health of cancer survivors. Current clinic-based performance status measures do not accurately capture the survivor's functioning, or rehabilitation and exercise needs. Our primary objective was to explore the feasibility of performing a performance-based functional assessment with brain tumour survivors as a means to inform needs for rehabilitation and exercise.

Methods: A feasibility study was conducted with survivors of brain and other neurological cancers attending new patient or follow-up clinics. Survivors were assessed using the Short Physical Performance Battery (SPPB), grip strength and Rosow-Breslau Physical Activity Self-Assessment (RSB).

Results: We approached 40 survivors with brain tumours, and 30 agreed to participate in the study. The SPPB was inversely correlated with Eastern Cooperative Oncology Group (ECOG) scores (r = -.73; p < .01), but scores on the SPPB for individuals classified as ECOG 1 ranged from 5 to 12 out of 12, indicating a large variability in functional scores within this ECOG grade.

Conclusion: Implementation of objective functional testing is feasible in the neuro-oncology outpatient clinic. The SPPB appears to best inform the functional status of survivors with brain tumours, facilitating more individualised exercise and rehabilitation referrals.

Keywords: brain neoplasms; exercise; glioma; rehabilitation.

MeSH terms

  • Adult
  • Aged
  • Astrocytoma / physiopathology*
  • Astrocytoma / rehabilitation
  • Brain Neoplasms / physiopathology*
  • Brain Neoplasms / rehabilitation
  • Cancer Survivors*
  • Feasibility Studies
  • Female
  • Functional Status
  • Glioblastoma / physiopathology*
  • Glioblastoma / rehabilitation
  • Hand Strength / physiology
  • Humans
  • Lower Extremity / physiopathology
  • Male
  • Middle Aged
  • Oligodendroglioma / physiopathology*
  • Oligodendroglioma / rehabilitation
  • Physical Functional Performance*
  • Postural Balance / physiology
  • Self Report
  • Walking Speed / physiology

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