Effect of exposure to high temperatures in the excretion of cadmium and lead

J Therm Biol. 2020 Apr:89:102545. doi: 10.1016/j.jtherbio.2020.102545. Epub 2020 Feb 17.

Abstract

Objective: This study aims to observe the effect on urine and sweat excretion levels of cadmium (Cd) and lead (Pb) in healthy men in a maximum incremental test until exhaustion and repeated exposure to heat.

Methods: twenty-nine adult men divided into control group (CG; n = 14) and experimental group (EG; n = 15) performing two maximum tests until exhaustion in normothermia (22 °C) and hyperthermia (42 °C). EG experienced 9 sessions of heat exposure at high temperatures (100 °C) (HEHT). After the nine sessions, the initial tests were repeated in both groups. Urine samples were collected before and after each test. After the hyperthermia tests, sweat samples were gathered.

Results: Urinary Cd increased after initial tests in GC and in hyperthermia in EG (p < 0.05). Urinary excretion of Pb rose after HEHT (p < 0.05). Pb in sweat was higher in EG than in CG after HEHT (p < 0.05).

Conclusion: Heat exercise and constant exposure to heat can be a valid method to increase the excretion of toxic metals.

MeSH terms

  • Cadmium / pharmacokinetics
  • Cadmium / urine*
  • Cutaneous Elimination
  • Exercise*
  • Heat-Shock Response*
  • Humans
  • Lead / pharmacokinetics
  • Lead / urine*
  • Male
  • Renal Elimination
  • Sweat / metabolism
  • Young Adult

Substances

  • Cadmium
  • Lead