A novel plant-derived compound is synergistic with 5-fluorouracil and has increased apoptotic activity through autophagy in the treatment of actinic keratoses
J Dermatolog Treat
.
2022 Feb;33(1):590-591.
doi: 10.1080/09546634.2020.1764905.
Epub 2020 May 20.
Authors
Cameron E West
1
,
Shawn G Kwatra
2
,
Justin Choi
3
,
Daniel Von Hoff
4
,
Laurence Booth
5
,
Paul Dent
5
Affiliations
1
Genzada Pharmaceuticals USA, Inc., Sterling, KS, USA.
2
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
3
University of Illinois College of Medicine, Chicago, IL, USA.
4
Translational Genomics Research Institute (TGEN), Phoenix, AZ, USA.
5
Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USA.
PMID:
32362152
DOI:
10.1080/09546634.2020.1764905
No abstract available
Publication types
Letter
MeSH terms
Autophagy
Fluorouracil / therapeutic use
Humans
Keratosis, Actinic* / drug therapy
Phytochemicals
Substances
Phytochemicals
Fluorouracil