Acute kidney injury and its impact on renal prognosis after robot-assisted laparoscopic radical prostatectomy

Int J Med Robot. 2020 Oct;16(5):1-7. doi: 10.1002/rcs.2117. Epub 2020 Jun 14.

Abstract

Background: This study assessed the incidence and impact of acute kidney injury (AKI) on renal prognosis in patients who underwent robot-assisted laparoscopic radical prostatectomy (RARP).

Methods: Medical records of 305 patients treated with RARP were retrospectively reviewed. The patients with postoperative AKIs were dichotomized into early AKI (immediately after surgery) and late AKI (1-7 days after surgery). The impact of AKIs and their risk factors were statistically assessed.

Results: Early and late AKI were observed in 143 (46.9%) and 12 (3.9%) patients, respectively. Hypertension and console time were independent risk factors for early AKI. Among the patients with preoperative eGFR ≥60 mL/min, the eGFR decline 12 months after surgery was significantly greater in patients with early AKI than that without early AKI (-6.8 vs -3.2 mL/min, P = .02).

Conclusions: Approximately half of patients developed early AKI after RARP. The patients with early AKI had reduced renal function 12 months after surgery.

Keywords: acute kidney injury; prostate cancer; robot-assisted laparoscopic radical prostatectomy.

MeSH terms

  • Acute Kidney Injury* / etiology
  • Humans
  • Kidney / physiology
  • Laparoscopy*
  • Male
  • Prognosis
  • Prostatectomy / adverse effects
  • Prostatic Neoplasms* / surgery
  • Retrospective Studies
  • Robotic Surgical Procedures* / adverse effects
  • Robotics*