Airway Protection-A Role for Vagal P2RY1 Receptors

Yalda Moayedi; Michael J Pitman; Joriene C de Nooij

doi:10.1016/j.cell.2020.04.006

Airway Protection-A Role for Vagal P2RY1 Receptors

Cell. 2020 Apr 30;181(3):509-511. doi: 10.1016/j.cell.2020.04.006.

Authors

Yalda Moayedi¹, Michael J Pitman², Joriene C de Nooij³

Affiliations

¹ Department of Physiology and Cellular Biophysics, Columbia University Medical Center, 1150 Saint Nicholas Ave, New York, NY 10032; Thompson Family Foundation Initiative at CUMC, New York, NY, USA.
² The Center for Voice and Swallowing, Department of Otolaryngology-Head & Neck Surgery, Columbia University Irving Medical Center/New York Presbyterian Hospital, 180 Fort Washington Ave, New York, NY 10032.
³ Department of Neurology, Columbia University Medical Center, 630 West 168(th) Street, New York, NY 10032; Columbia University Motor Neuron Center, Columbia University Medical Center, 650 West 168(th) Street, New York, NY 10032; Thompson Family Foundation Initiative at CUMC, New York, NY, USA. Electronic address: sd382@cumc.columbia.edu.

PMID: 32359432
DOI: 10.1016/j.cell.2020.04.006

Abstract

Recent events bring the importance of respiratory health to the forefront of our collective attention. In this issue of Cell, a new study by Prescott and Umans et al. reveals how a dedicated laryngeal sensory motor reflex circuit protects our airways from aspirated foods or liquids.

Publication types

Comment

MeSH terms

Larynx*
Reflex
Vagus Nerve*

Grants and funding

R01 NS106715/NS/NINDS NIH HHS/United States