Tyrosine phosphatase Shp2 regulates p115RhoGEF/Rho-dependent dendritic cell migration

Cell Mol Immunol. 2021 Mar;18(3):755-757. doi: 10.1038/s41423-020-0414-y. Epub 2020 Apr 29.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actin Depolymerizing Factors / genetics
  • Actin Depolymerizing Factors / metabolism
  • Animals
  • Cell Movement*
  • Dendritic Cells / cytology
  • Dendritic Cells / physiology*
  • Focal Adhesion Kinase 2 / genetics
  • Focal Adhesion Kinase 2 / metabolism
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism
  • Mice
  • Mice, Knockout
  • Phosphorylation
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11 / physiology*
  • Rho Guanine Nucleotide Exchange Factors / genetics
  • Rho Guanine Nucleotide Exchange Factors / metabolism*
  • rho GTP-Binding Proteins / genetics
  • rho GTP-Binding Proteins / metabolism*

Substances

  • Actin Depolymerizing Factors
  • Membrane Proteins
  • Mlc1 protein, mouse
  • Rho Guanine Nucleotide Exchange Factors
  • Focal Adhesion Kinase 2
  • Ptk2b protein, mouse
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11
  • Ptpn11 protein, mouse
  • rho GTP-Binding Proteins